Eosinophilic esophagitis (EoE) is a chronic condition that causes inflammation in the esophagus due to an overproduction of white blood cells called eosinophils. This inflammation can lead to symptoms like difficulty swallowing, chest pain, and food impaction. While dietary changes and other treatments can help manage EoE, biologic therapies have emerged as an effective treatment for reducing symptoms and inflammation. Understanding how biologics work and what you can do alongside them can help improve your quality of life.
What Are Biologics?
Biologics are a class of medications made from living organisms that target specific parts of the immune system. In the case of EoE, biologics work by blocking certain proteins that cause the overproduction of eosinophils, which are responsible for the inflammation in the esophagus. By reducing eosinophil activity, biologics can help control the symptoms of EoE and prevent further damage to the esophagus.
How Biologics Help Manage EoE
Biologics, such as monoclonal antibodies, are designed to target specific immune system pathways that contribute to the inflammation associated with EoE. These medications can help reduce the number of eosinophils in the esophagus and prevent them from causing further irritation. As a result, patients experience fewer flare-ups, less difficulty swallowing, and reduced pain and discomfort. Biologics can be particularly helpful for individuals whose EoE does not respond well to other treatments, such as corticosteroids or dietary changes.
What You Can Do Alongside Biologics
While biologic therapy can help manage the symptoms of EoE, it is important to remember that lifestyle changes and other treatments can further enhance the benefits. Dietary modifications, such as avoiding trigger foods like dairy, gluten, or certain allergens, can help reduce inflammation and prevent flare-ups. Working with a healthcare provider or dietitian can help you identify and eliminate food triggers from your diet.
Regular Monitoring and Follow-ups
Even when on biologic therapy, regular monitoring is essential to ensure that the treatment is working effectively. Doctors may recommend periodic endoscopies or other tests to check for improvements in esophageal inflammation. Staying consistent with follow-up appointments can help track your progress and make any necessary adjustments to your treatment plan.
Managing Stress and Overall Health
Stress can sometimes exacerbate EoE symptoms, so managing stress through techniques such as meditation, yoga, or exercise can contribute to better overall health. Maintaining a healthy lifestyle, including a balanced diet, regular physical activity, and enough sleep, can support the immune system and improve the effectiveness of biologic therapy.
Be Patient and Communicate with Your Healthcare Provider
It’s important to remember that biologic treatments may take time to show significant results. Being patient and communicating openly with your healthcare provider about any changes in symptoms or side effects will help optimize your treatment plan. Together, you and your doctor can adjust the approach to ensure that you’re getting the best care for your EoE.
Biologics offer a promising treatment for reducing the symptoms of eosinophilic esophagitis, but they work best when combined with a comprehensive management plan. By following a healthy lifestyle, staying on top of medical appointments, and working with your healthcare team, you can effectively manage EoE and improve your quality of life.